TY - JOUR

T1 - Validation of a screening tool for autism spectrum disorder in adults

T2 - a study protocol

AU - Parvaiz, Rizwan

AU - Al-Sayegh, Zainab

AU - Jacobsen, Peter Kristian

AU - Danielsen, Ida-Marie

AU - Videbech, Poul

N1 - Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

PY - 2022

Y1 - 2022

N2 - INTRODUCTION: Autism spectrum disorder (ASD) in adults is exhibiting an increase in prevalence, and a growing rate of referrals is observed from primary health professionals to specialised units. The heterogeneous clinical presentation and high prevalence of comorbidity seen in ASD challenges the case identification, emphasising the need for screening tools with a high validity and reliability. Previously, satisfactory psychometric properties of the Ritvo Autism Asperger Diagnostic Scale - Revised (RAADS-R) have been demonstrated, and it is a widely used screening tool in Denmark. Nevertheless, a validation of a Danish version of the RAADS-R has not been performed in a Danish population. To evaluate its clinical relevance, we aim to test the psychometric properties of a Danish translation of the RAADS-R (RAADS-R-DK) in an adult population.METHODS: We aim to test 200 ASD patients, 200 non-ASD psychiatric patients and 200 healthy controls. The results from the RAADS-R will be compared with the clinical diagnoses from interdisciplinary teams at specialised outpatient clinics.CONCLUSION: The aim of the study is to investigate the validity, reliability and clinical features of the RAADS-R-DK.FUNDING: Mental Health Center, TrygFonden, Sofiefonden and Takeda Pharma.CLINICALTRIALS: gov NCT05213286.

AB - INTRODUCTION: Autism spectrum disorder (ASD) in adults is exhibiting an increase in prevalence, and a growing rate of referrals is observed from primary health professionals to specialised units. The heterogeneous clinical presentation and high prevalence of comorbidity seen in ASD challenges the case identification, emphasising the need for screening tools with a high validity and reliability. Previously, satisfactory psychometric properties of the Ritvo Autism Asperger Diagnostic Scale - Revised (RAADS-R) have been demonstrated, and it is a widely used screening tool in Denmark. Nevertheless, a validation of a Danish version of the RAADS-R has not been performed in a Danish population. To evaluate its clinical relevance, we aim to test the psychometric properties of a Danish translation of the RAADS-R (RAADS-R-DK) in an adult population.METHODS: We aim to test 200 ASD patients, 200 non-ASD psychiatric patients and 200 healthy controls. The results from the RAADS-R will be compared with the clinical diagnoses from interdisciplinary teams at specialised outpatient clinics.CONCLUSION: The aim of the study is to investigate the validity, reliability and clinical features of the RAADS-R-DK.FUNDING: Mental Health Center, TrygFonden, Sofiefonden and Takeda Pharma.CLINICALTRIALS: gov NCT05213286.

KW - Adult

KW - Humans

KW - Ambulatory Care Facilities

KW - Autism Spectrum Disorder/diagnosis

KW - Psychometrics

KW - Referral and Consultation

KW - Reproducibility of Results

KW - Healthy Volunteers

M3 - Journal article

C2 - 36458608

VL - 69

JO - Danish Medical Journal

JF - Danish Medical Journal

SN - 2245-1919

IS - 12

M1 - A02220118

ER -